Polyglycolic acid
Polyglycolic acid is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Brand Name | Status | Last Update |
|---|---|---|
| perseris | New Drug Application | 2025-01-28 |
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Clinical Trials
39 clinical trials
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Indications Phases 4
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Alzheimer disease | D000544 | EFO_0000249 | F03 | — | 4 | — | — | — | 4 |
| Psychomotor agitation | D011595 | — | — | — | 2 | — | — | — | 2 |
| Aggression | D000374 | EFO_0003015 | — | — | 2 | — | — | — | 2 |
| Bipolar disorder | D001714 | EFO_0000289 | F30.9 | — | 1 | — | — | — | 1 |
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Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Polyglycolic acid |
| INN | polyglycolic acid |
| Description | Polyglycolide or poly(glycolic acid) (PGA), also spelled as polyglycolic acid, is a biodegradable, thermoplastic polymer and the simplest linear, aliphatic polyester. It can be prepared starting from glycolic acid by means of polycondensation or ring-opening polymerization. PGA has been known since 1954 as a tough fiber-forming polymer. Owing to its hydrolytic instability, however, its use has initially been limited. Currently polyglycolide and its copolymers (poly(lactic-co-glycolic acid) with lactic acid, poly(glycolide-co-caprolactone) with ε-caprolactone and poly (glycolide-co-trimethylene carbonate) with trimethylene carbonate) are widely used as a material for the synthesis of absorbable sutures and are being evaluated in the biomedical field.
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| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2107965 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | H1IL6F7KB8 (ChemIDplus, GSRS) |
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Safety
Black-box Warning
Black-box warning for: Perseris
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51 adverse events reported
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