Polyglycolic acid
Polyglycolic acid is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| perseris | New Drug Application | 2025-01-28 |
Indications
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Agency Specific
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Clinical
Clinical Trials
2514 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Colorectal neoplasms | D015179 | — | — | 2 | 9 | 6 | — | — | 16 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 1 | 2 | 3 | — | — | 6 |
| Neoplasms | D009369 | — | C80 | 1 | 3 | 2 | — | — | 5 |
| Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | 1 | 2 | 2 | — | — | 4 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | 1 | 2 | — | — | 3 |
| Lung neoplasms | D008175 | — | C34.90 | — | 2 | 1 | — | — | 2 |
| Carcinoma | D002277 | — | C80.0 | — | 1 | 1 | — | — | 2 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | — | 1 | 1 | — | — | 2 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | — | 1 | 1 | — | — | 2 |
| Insulinoma | D007340 | — | — | — | 1 | 1 | — | — | 1 |
Show 11 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Adenocarcinoma | D000230 | — | — | 2 | 5 | — | — | — | 7 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | 1 | 5 | — | — | — | 6 |
| Rectal neoplasms | D012004 | — | — | — | 4 | — | — | — | 4 |
| Esophageal neoplasms | D004938 | — | C15 | — | 3 | — | — | — | 3 |
| Head and neck neoplasms | D006258 | — | — | 1 | 2 | — | — | — | 2 |
| Squamous cell carcinoma | D002294 | — | — | 1 | 2 | — | — | — | 2 |
| Squamous cell neoplasms | D018307 | — | — | 1 | 2 | — | — | — | 2 |
| Uveitis | D014605 | EFO_1001231 | H20.9 | — | 1 | — | — | — | 1 |
| Arthritis | D001168 | EFO_0005856 | M05-M14 | — | 1 | — | — | — | 1 |
| Recurrence | D012008 | — | — | — | 1 | — | — | — | 1 |
Show 6 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pancreatic ductal carcinoma | D021441 | — | — | 1 | — | — | — | — | 1 |
| Non-small-cell lung carcinoma | D002289 | — | — | 1 | — | — | — | — | 1 |
| Small cell lung carcinoma | D055752 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Polyglycolic acid |
| INN | polyglycolic acid |
| Description | Polyglycolide or poly(glycolic acid) (PGA), also spelled as polyglycolic acid, is a biodegradable, thermoplastic polymer and the simplest linear, aliphatic polyester. It can be prepared starting from glycolic acid by means of polycondensation or ring-opening polymerization. PGA has been known since 1954 as a tough fiber-forming polymer. Owing to its hydrolytic instability, however, its use has initially been limited. Currently polyglycolide and its copolymers (poly(lactic-co-glycolic acid) with lactic acid, poly(glycolide-co-caprolactone) with ε-caprolactone and poly (glycolide-co-trimethylene carbonate) with trimethylene carbonate) are widely used as a material for the synthesis of absorbable sutures and are being evaluated in the biomedical field.
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| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 26009-03-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2107965 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | H1IL6F7KB8 (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
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Safety
Black-box Warning
Black-box warning for: Perseris
Adverse Events
Top Adverse Reactions
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50 adverse events reported
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