Polyglycolic acid
Polyglycolic acid is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
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EMA
Brand Name | Status | Last Update |
|---|---|---|
| perseris | New Drug Application | 2025-01-28 |
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Clinical Trials
37 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Glaucoma | D005901 | EFO_0000516 | H40 | — | — | 1 | 1 | — | 2 |
| Pancreatic fistula | D010185 | — | — | — | — | — | 1 | — | 1 |
| Fistula | D005402 | — | — | — | — | — | 1 | — | 1 |
| Gastrointestinal diseases | D005767 | — | — | — | — | — | 1 | — | 1 |
| Digestive system diseases | D004066 | EFO_0000405 | K92.9 | — | — | — | 1 | — | 1 |
| Laparotomy | D007813 | — | — | — | — | — | 1 | — | 1 |
| Surgical anastomosis | D000714 | — | — | — | — | — | 1 | — | 1 |
| Knee osteoarthritis | D020370 | EFO_0004616 | M17 | — | — | — | 1 | — | 1 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | — | — | 1 | — | 1 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | — | — | 1 | — | 1 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Gingival recession | D005889 | — | K06.0 | — | 2 | 1 | — | 2 | 4 |
| Brain stem infarctions | D020526 | EFO_1000847 | G46.3 | — | — | 1 | — | — | 1 |
| Sturge-weber syndrome | D013341 | Orphanet_3205 | Q85.89 | — | — | 1 | — | — | 1 |
| Klippel-trenaunay-weber syndrome | D007715 | EFO_0007334 | Q87.2 | — | — | 1 | — | — | 1 |
| Disease | D004194 | EFO_0000408 | R69 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Macular edema | D008269 | — | — | — | 1 | — | — | — | 1 |
| Edema | D004487 | — | R60.9 | — | 1 | — | — | — | 1 |
| Biliary liver cirrhosis | D008105 | — | K74.3 | 1 | 1 | — | — | — | 1 |
| Cholangitis | D002761 | HP_0030151 | K83.0 | 1 | 1 | — | — | — | 1 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | — | 1 | — | — | — | 1 |
| Periodontitis | D010518 | EFO_0000649 | K05.3 | — | 1 | — | — | — | 1 |
| Periodontal pocket | D010514 | EFO_1001393 | — | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hypersensitivity | D006967 | EFO_0003785 | T78.40 | 2 | — | — | — | — | 2 |
| Peanut hypersensitivity | D021183 | EFO_0007425 | — | 2 | — | — | — | — | 2 |
| Acute pain | D059787 | — | R52 | 1 | — | — | — | — | 1 |
| Retinal detachment | D012163 | EFO_0005773 | H33.2 | 1 | — | — | — | — | 1 |
| Melanoma | D008545 | — | — | 1 | — | — | — | — | 1 |
| Uveal neoplasms | D014604 | EFO_1001230 | — | 1 | — | — | — | — | 1 |
| Dissociative disorders | D004213 | — | F44.1 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hemorrhoids | D006484 | EFO_0009552 | K64 | — | — | — | — | 3 | 3 |
| Infections | D007239 | EFO_0000544 | — | — | — | — | — | 2 | 2 |
| Communicable diseases | D003141 | — | — | — | — | — | — | 2 | 2 |
| Postoperative pain | D010149 | — | G89.18 | — | — | — | — | 1 | 1 |
| Drug-related side effects and adverse reactions | D064420 | — | T88.7 | — | — | — | — | 1 | 1 |
| Inflammation | D007249 | MP_0001845 | — | — | — | — | — | 1 | 1 |
| Rupture | D012421 | — | — | — | — | — | — | 1 | 1 |
| Ventral hernia | D006555 | EFO_1001866 | K43 | — | — | — | — | 1 | 1 |
| Hernia | D006547 | — | K40-K46 | — | — | — | — | 1 | 1 |
| Wounds and injuries | D014947 | — | T14.8 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Polyglycolic acid |
| INN | polyglycolic acid |
| Description | Polyglycolide or poly(glycolic acid) (PGA), also spelled as polyglycolic acid, is a biodegradable, thermoplastic polymer and the simplest linear, aliphatic polyester. It can be prepared starting from glycolic acid by means of polycondensation or ring-opening polymerization. PGA has been known since 1954 as a tough fiber-forming polymer. Owing to its hydrolytic instability, however, its use has initially been limited. Currently polyglycolide and its copolymers (poly(lactic-co-glycolic acid) with lactic acid, poly(glycolide-co-caprolactone) with ε-caprolactone and poly (glycolide-co-trimethylene carbonate) with trimethylene carbonate) are widely used as a material for the synthesis of absorbable sutures and are being evaluated in the biomedical field.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2107965 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | H1IL6F7KB8 (ChemIDplus, GSRS) |
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Trends
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Safety
Black-box Warning
Black-box warning for: Perseris
Adverse Events
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